{"id":2466,"date":"2016-10-04T00:00:00","date_gmt":"2016-10-03T16:00:00","guid":{"rendered":"https:\/\/etdicwp2025.etdic.org.tw\/etdic\/%e5%9f%b9%e9%a4%8a%e3%81%97%e3%81%9f%e3%83%92%e3%83%88%e7%b7%9a%e7%b6%ad%e8%8a%bd%e7%b4%b0%e8%83%9e%e3%81%ae%e3%82%b3%e3%83%a9%e3%83%bc%e3%82%b2%e3%83%b3%e5%90%88%e6%88%90%e3%81%ab%e5%af%be%e3%81%99\/"},"modified":"2016-10-04T00:00:00","modified_gmt":"2016-10-03T16:00:00","slug":"%e5%9f%b9%e9%a4%8a%e3%81%97%e3%81%9f%e3%83%92%e3%83%88%e7%b7%9a%e7%b6%ad%e8%8a%bd%e7%b4%b0%e8%83%9e%e3%81%ae%e3%82%b3%e3%83%a9%e3%83%bc%e3%82%b2%e3%83%b3%e5%90%88%e6%88%90%e3%81%ab%e5%af%be%e3%81%99","status":"publish","type":"post","link":"https:\/\/etdicwp2025.etdic.org.tw\/etdic\/%e5%9f%b9%e9%a4%8a%e3%81%97%e3%81%9f%e3%83%92%e3%83%88%e7%b7%9a%e7%b6%ad%e8%8a%bd%e7%b4%b0%e8%83%9e%e3%81%ae%e3%82%b3%e3%83%a9%e3%83%bc%e3%82%b2%e3%83%b3%e5%90%88%e6%88%90%e3%81%ab%e5%af%be%e3%81%99\/","title":{"rendered":"\u57f9\u990a\u3057\u305f\u30d2\u30c8\u7dda\u7dad\u82bd\u7d30\u80de\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u5408\u6210\u306b\u5bfe\u3059\u308b\u4f0a\u8c46\u8d64\u6ca2\u6d77\u6d0b\u6df1\u5c64\u6c34\u306e\u52b9\u679c(Effects of deep seawater pumped at Izu-Akazawa on collagen synthesis in cultured human fibroblasts)"},"content":{"rendered":"<p>\u30b3\u30e9\u30fc\u30b2\u30f3\u306f\u7f8e\u5bb9\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u771f\u76ae\u30de\u30c8\u30ea\u3001\uff0c\u30af\u30b9\u6210\u5206\u306e\u30fc\u3064\u3067\uff0c\u305d\u306e\u5408\u6210\u306b\u306f\u30d3\u30bf\u30df\u30f3 C \u304c\u5fc5\u8981\u3067\u3042\u308b\uff0e \u8457\u8005\u3089\u306f\uff0c\u30d3\u30bf\u30df\u30f3C \u306e\u5b58\u5728\u4e0b\u3067\uff0c\u30d2\u30c8\u306e\u76ae\u819a\u7531\u6765\u306e\u7dda\u7dad\u82bd\u7d30\u80de\uff08\u4ee5\u4e0b\uff0cNB 1) \u3092\u4f0a\u8c46\u534a\u5cf6\u8d64\u6ca2\uff08\u6c34\u6df1800 m\uff09\u304b\u3089\u53d6\u6c34\u3055\u308c\u3066\u3044\u308b\u6d77\u6d0b\u6df1\u5c64\u6c34\uff08\u4ee5\u4e0b\uff0cDSW\uff09\u3068\u305d\u306e\u76f4\u4e0a\u306e\u8868\u9762 \u6d77\u6c34\uff08\u4ee5\u4e0b\uff0cssw\uff09\u3092\u6dfb\u52a0\u3057\u305f\u57f9\u5730\u3067\u57f9\u990a\u3057\uff0c\u30b3\u30e9\u30fc\u30b2\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u4ee5\u4e0b\uff0c\u30b3\u30e9\u30fc\u30b2\u30f3\uff09\u306e\u5408 \u6210\u91cf\u306e\u9055\u3044\u3092\u8abf\u3079\u305f\uff0e \u305d\u306e\u7d50\u679c\uff0cssw \u3067\u306f\u5bfe\u7167\u533a\u3067\u3042\u308bssw \u7121\u6dfb\u52a0\u533a\u3068\u6bd4\u30791.1 \u500d\u306b\u4e0a\u6607\u3057\u305f\u30b3 \u30e9\u30fc\u30b2\u30f3\u5408\u6210\u91cf\u304c\uff0cDSW \u3067\u306fDSW \u7121\u6dfb\u52a0\u533a\u3068\u6bd4\u30791.9 \u500d\u3068\uff0cssw \u3068\u6bd4\u8f03\u3057\u9855\u8457\u306b\u4e0a\u6607\u3057\u305f\uff0e \u3055 \u3089\u306b\uff0cDSW\u6dfb\u52a0\u533a\u306eNB1 \u3067\u306fI\u578b\u30b3\u30e9\u30fc\u30b2\u30f3\u30bf\u30f3\u30d1\u30af\u8cea\u907a\u4f1d\u5b50\uff08COL1) \u306e\u767a\u73fe\u304c\u65e9\u307e\u308b\u3053\u3068\u304c \u5224\u660e\u3057\u305f\uff0e<\/p>\n<p>  Collagen is an important composition of skin matrix to be paid attention in cosmetology. In the present study, effects of deep seawater on the synthesis of collagen in fibroblasts from human skins (NB1)were examined in culture. The fibroblasts were cultured in the presence of vitamin C (20ug\/mL) with 0 to 20%deep seawater (DSW) pumped from a depth of 800 m (5 km offshore) and in surface seawater (SSW) collected directly at the sea surface off Akazawa in Izu Peninsula, Shizuoka Prefecture, Japan. As a result, the collagen synthesis rose to 1.1 times in SSW compared with no added SSW. In contrast, the collagen synthesis remarkably rose to 1.9 times in DSW compared with no additive DSW. Other observations made during this study suggest that DSW promotes the expression of genes involved in Type I collagen synthesis (COL1)in the early stage in fibroblasts cultured with vitamin C.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30b3\u30e9\u30fc\u30b2\u30f3\u306f\u7f8e\u5bb9\u3092\u8003\u3048\u308b\u3046\u3048\u3067\u91cd\u8981\u306a\u771f\u76ae\u30de\u30c8\u30ea\u3001\uff0c\u30af\u30b9\u6210\u5206\u306e\u30fc\u3064\u3067\uff0c\u305d\u306e\u5408\u6210\u306b\u306f\u30d3\u30bf\u30df\u30f3 C \u304c\u5fc5\u8981\u3067\u3042\u308b\uff0e  [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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