{"id":2237,"date":"2017-08-11T00:00:00","date_gmt":"2017-08-10T16:00:00","guid":{"rendered":"https:\/\/etdicwp2025.etdic.org.tw\/etdic\/%e9%96%8b%e5%95%9f%e7%94%9f%e5%91%bd%e7%9a%84%e5%af%86%e7%a2%bc-%e6%b7%b1%e6%b5%b7%e5%a4%a9%e7%84%b6%e7%a4%a6%e7%89%a9%e8%b3%aa\/"},"modified":"2017-08-11T00:00:00","modified_gmt":"2017-08-10T16:00:00","slug":"%e9%96%8b%e5%95%9f%e7%94%9f%e5%91%bd%e7%9a%84%e5%af%86%e7%a2%bc-%e6%b7%b1%e6%b5%b7%e5%a4%a9%e7%84%b6%e7%a4%a6%e7%89%a9%e8%b3%aa","status":"publish","type":"post","link":"https:\/\/etdicwp2025.etdic.org.tw\/etdic\/%e9%96%8b%e5%95%9f%e7%94%9f%e5%91%bd%e7%9a%84%e5%af%86%e7%a2%bc-%e6%b7%b1%e6%b5%b7%e5%a4%a9%e7%84%b6%e7%a4%a6%e7%89%a9%e8%b3%aa\/","title":{"rendered":"\u958b\u555f\u751f\u547d\u7684\u5bc6\u78bc \u2013 \u6df1\u6d77\u5929\u7136\u7926\u7269\u8cea"},"content":{"rendered":"<p><u>\u6df1\u6d77\u5929\u7136\u7926\u7269\u8cea<\/u><\/p>\n<p> \u6df1\u5c64\u6d77\u6c34\u4e2d\u542b\u6709\u8d85\u904e80\u7a2e\u4ee5\u4e0a\u7684\u7926\u7269\u8cea\uff0c\u5176\u4e2d\u5305\u542b\u4e3b\u8981\u5143\u7d20\u8207\u5fae\u91cf\u5143\u7d20\uff0c\u800c\u900f\u904e\u8584\u819c\u904e\u6ffe\u6280\u8853\uff0c\u80fd\u5920\u4fdd\u7559\u6df1\u5c64\u6d77\u6c34\u4e2d\u5747\u8861\u591a\u6a23\u5316\u4e4b\u7926\u7269\u8cea\u8cc7\u6e90\uff0c\u5982\uff1a\u9382\u3001\u9240\u3001\u9223\u3001\u787c\u3001\u92a3\u3001\u92c5\u3001\u7852\u3001\u9376\u3001\u926c\u3001\u92f0\u3001\u77fd&hellip;\u7b49\uff0c\u800c\u6b64\u6df1\u6d77\u5929\u7136\u7926\u7269\u8cea\u5728\u8fd110\u591a\u5e74\u4f86\u570b\u5167\u5916\u5b78\u8005\u7684\u7814\u7a76\u4e2d\uff0c\u5df2\u986f\u73fe\u51fa\u6df1\u5c64\u6d77\u6c34\u5c0d\u65bc\u751f\u7269\u9ad4\u7684\u76ca\u8655\uff0c\u5982\uff1a\u6539\u5584\u7570\u4f4d\u6027\u76ae\u819a\u708e\u3001\u9810\u9632\u52d5\u8108\u7ca5\u72c0\u786c\u5316\u3001\u6297\u80a5\u80d6\u3001\u6297\u5e7d\u9580\u87ba\u65cb\u687f\u83cc\u3001\u6539\u5584\u5341\u4e8c\u6307\u8178\u6f70\u760d\u3001\u8abf\u7bc0\u8461\u8404\u7cd6\u4ee3\u8b1d\u3001\u5f71\u97ff\u8178\u9053\u83cc\u76f8\u5206\u4f48\u3001\u523a\u6fc0\u7c92\u7dda\u9ad4\u751f\u5408\u6210&#8230;\u7b49\u3002\u800c\u53f0\u7063\u6d77\u6d0b\u6df1\u5c64\u6c34\u516c\u53f8\u4e5f\u4e0d\u907a\u9918\u529b\u6295\u5165\u76f8\u95dc\u7814\u767c\uff0c\u6210\u679c\u5305\u542b\uff0c(1)\u4eba\u9ad4\u8a66\u9a57\u4e2d\u88dc\u5145\u6df1\u6d77\u7926\u7269\u8cea\u80fd\u964d\u4f4e\u7e3d\u81bd\u56fa\u9187\u8207\u4f4e\u5bc6\u5ea6\u8102\u86cb\u767d\u81bd\u56fa\u9187(LDL-C)\uff0c\u4e14\u80fd\u964d\u4f4e\u8102\u8cea\u904e\u6c27\u5316(Fu et al., 2012)\uff0c(2)\u900f\u904e\u52d5\u7269\u8a66\u9a57\u91d0\u6e05\u6df1\u6d77\u7926\u7269\u8cea\u80fd\u6d3b\u5316AMPK\u8def\u5f91\uff0c\u8207\u6291\u5236ACC\u7684\u78f7\u9178\u5316\u4f5c\u7528\uff0c\u800c\u9054\u5230\u5f71\u97ff\u8102\u8cea\u4ee3\u8b1d\uff0c\u9032\u800c\u964d\u4f4e\u8840\u6e05\u81bd\u56fa\u9187\u6fc3\u5ea6\u3001\u809d\u81df\u8102\u80aa\u84c4\u7a4d\u3001\u8207\u52d5\u8108\u8102\u80aa\u6591\u7d0b (fatty streaks)\uff0c\u9019\u4e9b\u6548\u679c\u4e0d\u50c5\u4f86\u81ea\u9382\u96e2\u5b50\uff0c\u5176\u4ed6\u7926\u7269\u8cea\u6216\u5fae\u91cf\u5143\u7d20\u4e5f\u53ef\u80fd\u53c3\u8207\u8ca2\u737b(Sheu et al., 2013)\uff0c(3)\u98f2\u7528\u6df1\u6d77\u7926\u7269\u8cea\u80fd\u964d\u4f4e\u539f\u767c\u6027\u9ad8\u8840\u58d3\u5927\u9f20\u7684\u6536\u7e2e\u58d3\u8207\u8212\u5f35\u58d3\uff0c\u6548\u679c\u8207\u5229\u5c3f\u5291 (lasix) \u76f8\u7576(Sheu et al., 2013)\uff0c(4)\u6539\u5584STZ\u8a98\u5c0e\u7684\u7cd6\u5c3f\u75c5\u9f20\u76f8\u95dc\u4f75\u767c\u75c7\uff0c\u5982\u4fc3\u9032\u5fc3\u808c\u7d30\u80de\u589e\u751f\u3001\u6e1b\u7de9\u809d\u7d30\u80de\u51cb\u4ea1\uff0c\u8207\u964d\u4f4e\u7cd6\u5c3f\u75c5\u9f20\u6b7b\u4ea1\u7387\uff0c\u63d0\u5347\u5b58\u6d3b\u7387(Hsu et al., 2015\uff1bLiao et al., 2016)\u3002(5)\u88dc\u5145\u6df1\u6d77\u7926\u7269\u8cea\u80fd\u6709\u6548\u6e1b\u7de9\u8840\u7ba1\u5167\u76ae\u7d30\u80de\u904e\u5ea6\u589e\u751f\uff0c\u4ee5\u53ca\u964d\u4f4e\u8840\u7ba1\u5167\u76ae\u589e\u751f\u76f8\u95dc\u86cb\u767d\u8868\u73fe\u91cf(Li et al., 2014)\uff0c(6)\u4e0d\u50c5\u589e\u52a0\u6458\u9664\u5375\u5de2\u7684\u65e9\u8001\u5316\u5c0f\u9f20 (OVX-SAMP8) \u7684\u9aa8\u5bc6\u5ea6\u8207\u6291\u5236\u9e7c\u6027\u78f7\u9178\u9176\u6d3b\u6027\uff0c\u9084\u5728\u9aa8\u9ad3\u57fa\u8cea\u7d30\u80de\u89c0\u5bdf\u5230\u6df1\u6d77\u7926\u7269\u80fd\u660e\u986f\u4fc3\u9032\u9aa8\u5206\u5316\u4f5c\u7528(Liu  <\/p>\n<p>et al <\/p>\n<p>., 2013)\uff0c(7)\u904b\u52d5\u524d\u88dc\u5145\u6df1\u6d77\u7926\u7269\u8cea\u53ef\u589e\u52a0\u904b\u52d5\u8868\u73fe\uff0c\u904b\u52d5\u5f8c\u88dc\u5145\u6df1\u6d77\u7926\u7269\u8cea\u6e1b\u5c11\u808c\u8089\u640d\u50b7(Hou et al., 2013\uff1bWang et al., 2014)\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6df1\u6d77\u5929\u7136\u7926\u7269\u8cea \u6df1\u5c64\u6d77\u6c34\u4e2d\u542b\u6709\u8d85\u904e80\u7a2e\u4ee5\u4e0a\u7684\u7926\u7269\u8cea\uff0c\u5176\u4e2d\u5305\u542b\u4e3b\u8981\u5143\u7d20\u8207\u5fae\u91cf\u5143\u7d20\uff0c\u800c\u900f\u904e\u8584\u819c\u904e\u6ffe\u6280\u8853\uff0c\u80fd\u5920\u4fdd\u7559 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